Janus Henderson's head of EMEA, LatAm and AsiaPac distribution has left the firm to "take some time out with his family" and "pursue other opportunities".
Greg Jones left Janus Henderson at the end of October.
His responsibilties have been assumed by the global distribution leadership team lead by Suzanne Cain, global head of distribution, who joined the firm in May this year.
A spokesperson for Janus Henderson commented: "Globally our client needs are changing, reshaped by regulation, new technologies and new product preferences in uncertain markets.
"As a firm, Janus Henderson is focused on meeting the needs of its clients, recognising that our value as active managers requires providing our clients the right solutions, investment outcomes, and overall experience."
They added: "We are extremely grateful for [Greg's] commitment and contribution to the Janus Henderson distribution organisation. We wish him success in future endeavors."
Jones joined Henderson in 2009 following the acquisition of New Star Asset Management, where he was a founder of the company's UK investment funds business and managing director of New Star International Investment Funds.
In September, Janus Henderson made three new hires to its UK distribution team from rival asset managers.
Mark Buckley joined from Kames Capital as UK South East associate director, Christopher Garcia was hired from Old Mutual Wealth as business development manager and Dipesh Amin joined from Aberdeen Standard Investments as UK sales executive.