Brad Tank, chief investment officer - fixed income, Neuberger Berman, discusses the major transition in central bank philosophy that has appeared in recent weeks.
Rob Burnett, head of European equities, Neptune
Compounding the gloomy outlook among investors is the ratcheting up of event risk. Brexit is looming largest, driving down sterling and threatening a period of sustained instability.
In the second part of this special Big Question, managers assess the risks and rewards of investing in this sector in the current climate.
Could face costly regulatory barriers